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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
14.55
Human Site:
S139
Identified Species:
26.67
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
S139
Y
S
E
N
K
T
G
S
F
L
I
R
E
S
E
Chimpanzee
Pan troglodytes
XP_518702
505
58217
S139
Y
S
E
N
K
T
G
S
F
L
I
R
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
A139
Y
S
K
N
K
T
G
A
F
L
I
R
E
S
E
Dog
Lupus familis
XP_539091
505
57709
A143
Y
S
G
N
Q
T
G
A
F
L
I
R
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
A146
Y
S
E
N
Q
T
G
A
F
L
I
R
E
S
E
Rat
Rattus norvegicus
Q62662
506
58147
A140
Y
S
E
N
Q
T
G
A
F
L
I
R
E
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
T171
C
H
G
N
C
R
G
T
F
L
I
R
E
S
E
Frog
Xenopus laevis
P13406
537
60828
T172
S
F
G
N
P
R
G
T
Y
L
I
R
E
S
E
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
H137
R
D
D
V
K
V
K
H
Y
K
I
R
K
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
A153
L
P
E
N
E
H
G
A
F
L
I
R
D
S
E
Honey Bee
Apis mellifera
XP_396043
451
51726
K112
I
P
S
N
Y
V
A
K
L
K
S
I
E
A
E
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
A147
H
T
L
N
E
H
G
A
F
L
V
R
D
S
E
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
S167
L
S
Q
N
E
H
G
S
F
L
I
R
E
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
100
86.6
80
N.A.
86.6
86.6
N.A.
N.A.
60
53.3
20
N.A.
60
20
46.6
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
66.6
46.6
N.A.
80
26.6
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
47
0
0
0
0
0
8
0
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
0
0
16
0
8
% D
% Glu:
0
0
39
0
24
0
0
0
0
0
0
0
77
0
93
% E
% Phe:
0
8
0
0
0
0
0
0
77
0
0
0
0
0
0
% F
% Gly:
0
0
24
0
0
0
85
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
24
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
85
8
0
0
0
% I
% Lys:
0
0
8
0
31
0
8
8
0
16
0
0
8
0
0
% K
% Leu:
16
0
8
0
0
0
0
0
8
85
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
24
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
16
0
0
0
0
0
93
0
0
0
% R
% Ser:
8
54
8
0
0
0
0
24
0
0
8
0
0
85
0
% S
% Thr:
0
8
0
0
0
47
0
16
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
16
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _